EPS8 Polyclonal Antibody

• Background:

  EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8) is a Protein Coding gene. Diseases associated with EPS8 include Deafness, Autosomal Recessive 102 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are Development ERBB-family signaling and Tyrosine Kinases / Adaptors. EPS8 encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of EPS8 have been observed but have not been thoroughly characterized.

• Description:

  Rabbit Anti-EPS8 Polyclonal Antibody

• Product Name Alternative:

  Epidermal growth factor receptor kinase substrate 8

• Gene ID:

  2059

• Accession Number:

  Q12929

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human EPS8 protein at amino acid sequence of 130-210

• Clonality:

  Polyclonal

• Tag:

  EPS8

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  90kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of EPS8 protein

• Observed Molecular Weight:

  90

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Epidermal growth factor receptor kinase substrate 8

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q12929

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG