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DYLT1 Polyclonal Antibody

CAT: 0749-ABP58436-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58436-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DYNLT1 encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The dynein light chain Tctex-type 1 regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
Rabbit Anti-DYLT1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Dynein light chain Tctex-type 1; Protein CW-1; T-complex testis-specific protein 1 homolog
Gene ID
6993
Accession Number
P63172
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human DYLT1 protein
Clonality
Polyclonal
Tag
DYLT1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
12kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DYLT1 protein
Observed Molecular Weight
12
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Dynein light chain Tctex-type 1; Protein CW-1; T-complex testis-specific protein 1 homolog
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P63172
Isotype
Rabbit IgG

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