DSCAM Polyclonal Antibody

CAT: 0749-ABP58424-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58424-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DSCAM is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs) and is involved in human central and peripheral nervous system development. DSCAM is a candidate for Down syndrome and congenital heart disease (DSCHD) . A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. DSCAM (DS Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with DSCAM include Down Syndrome-Related Congenital Heart Disease and Down Syndrome. Among its related pathways are Cell junction organization and Guidance Cues and Growth Cone Motility. An important paralog of this gene is DSCAML1.
Description
Rabbit Anti-DSCAM Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Down syndrome cell adhesion molecule; CHD2
Gene ID
1826
Accession Number
O60469
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human DSCAM protein
Clonality
Polyclonal
Tag
DSCAM
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
221kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DSCAM protein
Observed Molecular Weight
221
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Down syndrome cell adhesion molecule; CHD2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O60469
Isotype
Rabbit IgG

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