DBLOH Polyclonal Antibody

• Background :

  DIABLO encodes an inhibitor of apoptosis protein (IAP) -binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in DIABLO is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Description :

  Rabbit Anti-DBLOH Polyclonal Antibody

• Product Name Alternative :

  Diablo homolog; mitochondrial; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; Smac

• Gene ID :

  56616

• Accession Number :

  Q9NR28

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human DBLOH protein

• Clonality :

  Polyclonal

• Tag :

  DBLOH

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  26kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of DBLOH protein

• Observed Molecular Weight :

  26

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Diablo homolog; mitochondrial; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; Smac

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q9NR28

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG