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CRADD Polyclonal Antibody

CAT: 0749-ABP58262-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58262-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CRADD encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation inCRADD was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-CRADD Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Death domain-containing protein CRADD; Caspase and RIP adapter with death domain; RIP-associated protein with a death domain
Gene ID
8738
Accession Number
P78560
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human CRADD protein at amino acid sequence of 30-110
Clonality
Polyclonal
Tag
CRADD
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
21kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CRADD protein
Observed Molecular Weight
21
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Death domain-containing protein CRADD; Caspase and RIP adapter with death domain; RIP-associated protein with a death domain
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P78560
Isotype
Rabbit IgG

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