COX2 Polyclonal Antibody

• Background :

  MT-CO2 (Mitochondrially Encoded Cytochrome C Oxidase II) is a Protein Coding gene. Diseases associated with MT-CO2 include Mitochondrial Complex Iv Deficiency and Familial Colorectal Cancer. Among its related pathways are Metabolism and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

• Description :

  Rabbit Anti-COX2 Polyclonal Antibody

• Product Name Alternative :

  Cytochrome c oxidase subunit 2; Cytochrome c oxidase polypeptide II

• Gene ID :

  4513

• Accession Number :

  P00403

• Reactivity :

  Human, Rat

• Immunogen :

  Synthesized peptide derived from part region of human COX2 protein at amino acid sequence of 40-120

• Clonality :

  Polyclonal

• Tag :

  COX2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  24kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of COX2 protein

• Observed Molecular Weight :

  24

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Cytochrome c oxidase subunit 2; Cytochrome c oxidase polypeptide II

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P00403

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG