COL8A2 Polyclonal Antibody

• Background :

  COL8A2 (Collagen Type VIII Alpha 2 Chain) is a Protein Coding gene. Diseases associated with COL8A2 include Corneal Dystrophy, Posterior Polymorphous 2 and Corneal Dystrophy, Fuchs Endothelial, 1. Among its related pathways are Phospholipase-C Pathway and Collagen chain trimerization. This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in COL8A2 are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.

• Description :

  Rabbit Anti-COL8A2 Polyclonal Antibody

• Product Name Alternative :

  Collagen alpha-2 (VIII) chain; Endothelial collagen

• Gene ID :

  1296

• Accession Number :

  P25067

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from part region of human COL8A2 protein at amino acid sequence of 611-660

• Clonality :

  Polyclonal

• Tag :

  COL8A2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  80kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of COL8A2

• Observed Molecular Weight :

  80

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000

• Other Product Names :

  Collagen alpha-2 (VIII) chain; Endothelial collagen

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P25067

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG