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CNTFR Polyclonal Antibody

CAT: 0749-ABP58211-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58211-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CNTFR encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in CNTFR may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for CNTFR.
Description
Rabbit Anti-CNTFR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha
Gene ID
1271
Accession Number
P26992
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human CNTFR protein
Clonality
Polyclonal
Tag
CNTFR
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
40kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CNTFR protein
Observed Molecular Weight
40
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P26992
Isotype
Rabbit IgG

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