CLCN5 Polyclonal Antibody

• Background :

  CLCN5 encodes a member of the ClC family of chloride ion channels and ion transporters. The Chloride Voltage-Gated Channel 5 is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

• Description :

  Rabbit Anti-CLCN5 Polyclonal Antibody

• Product Name Alternative :

  H (+) /Cl (-) exchange transporter 5; Chloride channel protein 5; ClC-5; Chloride transporter ClC-5

• Gene ID :

  1184

• Accession Number :

  P51795

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from part region of human CLCN5 protein

• Clonality :

  Polyclonal

• Tag :

  CLCN5

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  82kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of CLCN5 protein

• Observed Molecular Weight :

  82

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  H (+) /Cl (-) exchange transporter 5; Chloride channel protein 5; ClC-5; Chloride transporter ClC-5

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P51795

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG