CLCN2 Polyclonal Antibody

CAT: 0749-ABP58181-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58181-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CLCN2 (Chloride Voltage-Gated Channel 2) is a Protein Coding gene. Diseases associated with CLCN2 include Leukoencephalopathy With Ataxia and Epilepsy, Idiopathic Generalized 11. Among its related pathways are Hepatic ABC Transporters and Activation of cAMP-Dependent PKA. CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in CLCN2 may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for CLCN2.
Description
Rabbit Anti-CLCN2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Chloride channel protein 2; ClC-2
Gene ID
1181
Accession Number
P51788
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human CLCN2 protein
Clonality
Polyclonal
Tag
CLCN2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
98kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CLCN2 protein
Observed Molecular Weight
98
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Chloride channel protein 2; ClC-2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P51788
Isotype
Rabbit IgG

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