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ARHG6 Polyclonal Antibody

CAT: 0749-ABP57810-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57810-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ARHGEF6 (Rac/Cdc42 Guanine Nucleotide Exchange Factor 6) is a Protein Coding gene. Diseases associated with ARHGEF6 include X-Linked Non-Specific Intellectual Disability and Supraglottis Cancer. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in ARHGEF6 can cause X-chromosomal non-specific cognitive disability.
Description
Rabbit Anti-ARHG6 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Rho guanine nucleotide exchange factor 6; Alpha-Pix; COOL-2; PAK-interacting exchange factor alpha; Rac/Cdc42 guanine nucleotide exchange factor 6
Gene ID
9459
Accession Number
Q15052
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human ARHG6 protein at amino acid sequence of 580-660
Clonality
Polyclonal
Tag
ARHG6
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
85kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ARHG6 protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Rho guanine nucleotide exchange factor 6; Alpha-Pix; COOL-2; PAK-interacting exchange factor alpha; Rac/Cdc42 guanine nucleotide exchange factor 6
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q15052
Isotype
Rabbit IgG

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