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AKAP6 Polyclonal Antibody

CAT: 0749-ABP57736-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57736-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
AKAP6 (A-Kinase Anchoring Protein 6) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP6 encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.
Description
Rabbit Anti-AKAP6 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
A-kinase anchor protein 6; AKAP-6; A-kinase anchor protein 100 kDa; AKAP 100; Protein kinase A-anchoring protein 6; PRKA6; mAKAP
Gene ID
9472
Accession Number
Q13023
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from part region of human AKAP6 protein at amino acid sequence of 30-110
Clonality
Polyclonal
Tag
AKAP6
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
255kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of AKAP6 protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
A-kinase anchor protein 6; AKAP-6; A-kinase anchor protein 100 kDa; AKAP 100; Protein kinase A-anchoring protein 6; PRKA6; mAKAP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13023
Isotype
Rabbit IgG

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