AKAP4 Polyclonal Antibody

CAT: 0749-ABP57735-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57735-01Size:30 µL
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Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4 encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. AKAP4 (A-Kinase Anchoring Protein 4) is a Protein Coding gene. Diseases associated with AKAP4 include Retinitis Pigmentosa 70. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling.
Description
Rabbit Anti-AKAP4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
A-kinase anchor protein 4; AKAP-4; A-kinase anchor protein 82 kDa; AKAP 82; hAKAP82; Major sperm fibrous sheath protein; HI; Protein kinase A-anchoring protein 4; PRKA4
Gene ID
8852
Accession Number
Q5JQC9
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human AKAP4 protein at amino acid sequence of 430-510
Clonality
Polyclonal
Tag
AKAP4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
93kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of AKAP4 protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
A-kinase anchor protein 4; AKAP-4; A-kinase anchor protein 82 kDa; AKAP 82; hAKAP82; Major sperm fibrous sheath protein; HI; Protein kinase A-anchoring protein 4; PRKA4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5JQC9
Isotype
Rabbit IgG

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