AFF4 Polyclonal Antibody

• Background:

  AFF4 (AF4/FMR2 Family Member 4) is a Protein Coding gene. Diseases associated with AFF4 include Chops Syndrome and Lymphoblastic Leukemia. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Gene Expression. The protein encoded by AFF4 belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving AFF4 and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.

• Description:

  Rabbit Anti-AFF4 Polyclonal Antibody

• Product Name Alternative:

  AF4/FMR2 family member 4; ALL1-fused gene from chromosome 5q31 protein; Protein AF-5q31; Major CDK9 elongation factor-associated protein

• Gene ID:

  27125

• Accession Number:

  Q9UHB7

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human AFF4 protein at amino acid sequence of 30-110

• Clonality:

  Polyclonal

• Tag:

  AFF4

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  127kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of AFF4 protein

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  AF4/FMR2 family member 4; ALL1-fused gene from chromosome 5q31 protein; Protein AF-5q31; Major CDK9 elongation factor-associated protein

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q9UHB7

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG