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ACO2 Polyclonal Antibody

CAT: 0749-ABP57686-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57686-01Size:30 µL
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Background
ACO2 (Aconitase 2) is a Protein Coding gene. Diseases associated with ACO2 include Infantile Cerebellar-Retinal Degeneration and Optic Atrophy 9. Among its related pathways are Metabolism and Citrate cycle (TCA cycle) . The protein encoded by ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.
Description
Rabbit Anti-ACO2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase
Gene ID
50
Accession Number
Q99798
Reactivity
Human, Mouse, Rat, Canine
Immunogen
Synthesized peptide derived from part region of human ACO2 protein at amino acid sequence of 421-470
Clonality
Polyclonal
Tag
ACO2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
90kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ACO2
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000.Not yet tested in other applications.
Other Product Names
Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99798
Isotype
Rabbit IgG

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