Products for Research Use Only

MIB1 Polyclonal Antibody

CAT: 0749-ABP57540-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57540-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1) .
Description
Rabbit Anti-MIB1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MIB1; DIP1; KIAA1323; ZZANK2
Gene ID
57534
Accession Number
Q86YT6
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide from human protein at AA range: 901-950
Clonality
Polyclonal
Tag
Mindbomb homolog 1 (Drosophila)
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
130kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous MIB1 protein.
Observed Molecular Weight
130
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-2000; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
MIB1; DIP1; KIAA1323; ZZANK2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q86YT6
Isotype
Rabbit IgG