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C8 β Polyclonal Antibody

CAT: 0749-ABP57525-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57525-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C8B (complement C8 beta chain) encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-C8 β Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Complement component C8 beta chain; Complement component 8 subunit beta
Gene ID
732
Accession Number
P07358
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from C8 β at AA range: 371-420
Clonality
Polyclonal
Tag
C8 β
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
C8 β Polyclonal Antibody detects endogenous levels of C8 β.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000
Other Product Names
Complement component C8 beta chain; Complement component 8 subunit beta
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P07358
Isotype
Rabbit IgG

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