Products for Research Use Only

TyrRS Polyclonal Antibody

CAT: 0749-ABP57523-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57523-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Description
Rabbit Anti-TyrRS Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Tyrosine--tRNA ligase, cytoplasmic; Tyrosyl-tRNA synthetase; TyrRS
Gene ID
8565
Accession Number
P54577
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from TyrRS at AA range: 451-500
Clonality
Polyclonal
Tag
TyrRS
Applications
WB, IHC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
60kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
TyrRS Polyclonal Antibody detects endogenous levels of TyrRS.
Observed Molecular Weight
60
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:10000-20000
Other Product Names
Tyrosine--tRNA ligase, cytoplasmic; Tyrosyl-tRNA synthetase; TyrRS
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P54577
Isotype
Rabbit IgG