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PTH-rP Polyclonal Antibody

CAT: 0749-ABP57515-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57515-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by PTHLH (parathyroid hormone like hormone) is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in PTHLH are associated with brachydactyly type E2 (BDE2) . Alternatively spliced transcript variants have been found for PTHLH. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.
Description
Rabbit Anti-PTH-rP Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Parathyroid hormone-related protein; PTH-rP; PTHrP; Parathyroid hormone-like protein; PLP
Gene ID
5744
Accession Number
P12272
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from PTH-rP at AA range: 101-150
Clonality
Polyclonal
Tag
PTH-rP
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
25kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PTH-rP Polyclonal Antibody detects endogenous levels of PTH-rP.
Observed Molecular Weight
25
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
Parathyroid hormone-related protein; PTH-rP; PTHrP; Parathyroid hormone-like protein; PLP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P12272
Isotype
Rabbit IgG

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