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PTH-rP Polyclonal Antibody

CAT: 0965-JOT-AP07480-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07480-01Size:20 µL
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Background
The protein encoded by PTHLH (parathyroid hormone like hormone) is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in PTHLH are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for PTHLH. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.
CAS Number
9007-83-4
Synonyms
Parathyroid hormone-related protein (PTH-rP) (PTHrP) (Parathyroid hormone-like protein) (PLP) [Cleaved into: PTHrP[1-36]; PTHrP[38-94]; Osteostatin (PTHrP[107-139])]
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PTHLH. AA range:101-150
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
20194
Antibody Type
Primary antibody
Isotype
IgG

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