ETBR Polyclonal Antibody

• Background :

  The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for EDNRB.

• Description :

  Rabbit Anti-ETBR Polyclonal Antibody

• Product Name Alternative :

  Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type

• Gene ID :

  1910

• Accession Number :

  P24530

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthesized peptide derived from ETBR at AA range: 31-80

• Clonality :

  Polyclonal

• Tag :

  ETBR

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  50kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  ETBR Polyclonal Antibody detects endogenous levels of ETBR.

• Observed Molecular Weight :

  50

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-2000; ELISA 1:10000-20000; IF 1:50-200

• Other Product Names :

  Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P24530

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG