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ETBR Polyclonal Antibody

CAT: 0749-ABP57511-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57511-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for EDNRB.
Description
Rabbit Anti-ETBR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type
Gene ID
1910
Accession Number
P24530
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from ETBR at AA range: 31-80
Clonality
Polyclonal
Tag
ETBR
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
50kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ETBR Polyclonal Antibody detects endogenous levels of ETBR.
Observed Molecular Weight
50
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-2000; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P24530
Isotype
Rabbit IgG

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