TLK1 Polyclonal Antibody

• Background:

  The protein encoded by TLK1 (tousled like kinase 1) is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for TLK1.

• Description:

  Rabbit Anti-TLK1 Polyclonal Antibody

• Product Name Alternative:

  TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1

• Gene ID:

  9874

• Accession Number:

  Q9Y4F6

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from human TLK1 around the non-phosphorylation site of S764

• Clonality:

  Polyclonal

• Tag:

  Serine threonine-protein kinase tousled-like 1

• Applications:

  IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  TLK1 Polyclonal Antibody detects endogenous levels of TLK1 protein.

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications

• Other Product Names:

  TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q9Y4F6

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG