TLK1 Polyclonal Antibody

CAT: 0749-ABP57117-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP57117-01Size:30 µL
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Background
The protein encoded by TLK1 (tousled like kinase 1) is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for TLK1.
Description
Rabbit Anti-TLK1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1
Gene ID
9874
Accession Number
Q9Y4F6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human TLK1 around the non-phosphorylation site of S764
Clonality
Polyclonal
Tag
Serine threonine-protein kinase tousled-like 1
Applications
IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
TLK1 Polyclonal Antibody detects endogenous levels of TLK1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications
Other Product Names
TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y4F6
Isotype
Rabbit IgG

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