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P311 Polyclonal Antibody

CAT: 0749-ABP57019-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57019-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.
Description
Rabbit Anti-P311 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
NREP; C5orf13; P311; Neuronal regeneration-related protein; Neuronal protein 3.1; Protein p311
Gene ID
9315
Accession Number
Q16612
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human P311 at AA range: 30-110
Clonality
Polyclonal
Tag
Neuronal regeneration-related protein
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
P311 Polyclonal Antibody detects endogenous levels of P311 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
NREP; C5orf13; P311; Neuronal regeneration-related protein; Neuronal protein 3.1; Protein p311
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q16612
Isotype
Rabbit IgG

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