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BMP-8 Polyclonal Antibody

CAT: 0749-ABP56233-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56233-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BMP8B (bone morphogenetic protein 8b) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of BMP8B may be downregulated in pancreatic cancer. BMP8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
Description
Rabbit Anti-BMP-8 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2; BMP8A; Bone morphogenetic protein 8A; BMP-8A
Gene ID
656
Accession Number
P34820/Q7Z5Y6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human BMP-8
Clonality
Polyclonal
Tag
Bone morphogenetic protein 8A
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
BMP-8 Polyclonal Antibody detects endogenous levels of BMP-8 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2; BMP8A; Bone morphogenetic protein 8A; BMP-8A
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P34820
Isotype
Rabbit IgG

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