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SETMAR Polyclonal Antibody

CAT: 0749-ABP56158-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56158-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SETMAR (SET domain and mariner transposase fusion gene) encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. SETMAR exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Description
Rabbit Anti-SETMAR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SETMAR; Histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein; HsMar1; Metnase
Gene ID
6419
Accession Number
Q53H47
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human SETMAR
Clonality
Polyclonal
Tag
Histone-lysine N-methyltransferase SETMAR
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
SETMAR; Histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein; HsMar1; Metnase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q53H47
Isotype
Rabbit IgG

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