Products for Research Use Only
RegisterLogin

AIRE-1 Polyclonal Antibody

CAT: 0749-ABP54773-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP54773-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED) .
Description
Rabbit Anti-AIRE-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
AIRE; APECED; Autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein
Gene ID
326
Accession Number
O43918
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
Clonality
Polyclonal
Tag
Autoimmune regulator
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
50kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
AIRE-1 Polyclonal Antibody detects endogenous levels of AIRE-1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
AIRE; APECED; Autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O43918
Isotype
Rabbit IgG

Related Products

CatalogName
ANT-10146-100ugAIRE Polyclonal Antibody
ANT-10146-50ugAIRE Polyclonal Antibody
ABP54772-01AIRE-1 (phospho Ser156) Polyclonal Antibody
PPT-10465Human AIRE Recombinant Protein
KTE60636-01Human Autoimmune regulator (AIRE) ELISA Kit
KTE70434-01ELISA kit for Mouse Autoimmune regulator (AIRE)
ABP57018-01AIRP Polyclonal Antibody
ABP53355-01SIRP-α1/β1 Polyclonal Antibody
ABP57468-01Caspase-1 Polyclonal Antibody
ABP51436-01GluR-1 Polyclonal Antibody

Alternative Products

CatalogName
JOT-AP00312-01AIRE-1 Polyclonal Antibody
APRab06708-01AIRE-1 Rabbit Polyclonal Antibody
MBS9449620-01AIRE-1 Polyclonal Conjugated Antibody
GTR18044959-01AIRE polyclonal antibody
C10123-01AIRE-1 Antibody

Popular Products