Products for Research Use Only

GlyRβ Polyclonal Antibody

CAT: 0749-ABP54567-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54567-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-GlyRβ Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit
Gene ID
2743
Accession Number
P48167
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human GlyRβ at AA rangle: 180-260
Clonality
Polyclonal
Tag
Glycine receptor subunit beta
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
56kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GlyRβ Polyclonal Antibody detects endogenous levels of GlyRβ protein.
Observed Molecular Weight
56
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P48167
Isotype
Rabbit IgG