AMPD3 Polyclonal Antibody

• Background:

  AMPD3 encodes a member of the AMP deaminase gene family. The adenosine monophosphate deaminase 3 is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

• Description:

  Rabbit Anti-AMPD3 Polyclonal Antibody

• Product Name Alternative:

  AMPD3; AMP deaminase 3; AMP deaminase isoform E; Erythrocyte AMP deaminase

• Gene ID:

  272

• Accession Number:

  Q01432

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from the Internal region of human AMPD3 at AA rangle: 280-360

• Clonality:

  Polyclonal

• Tag:

  AMP deaminase 3

• Applications:

  IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  AMPD3 Polyclonal Antibody detects endogenous levels of AMPD3 protein.

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200

• Other Product Names:

  AMPD3; AMP deaminase 3; AMP deaminase isoform E; Erythrocyte AMP deaminase

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q01432

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG