LARG Polyclonal Antibody

CAT: 0749-ABP54334-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54334-01Size:30 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The Rho guanine nucleotide exchange factor 12 may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-LARG Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF
Gene ID
23365
Accession Number
Q9NZN5
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human LARG at AA rangle: 420-500
Clonality
Polyclonal
Tag
Rho guanine nucleotide exchange factor 12
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
173kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
LARG Polyclonal Antibody detects endogenous levels of LARG protein.
Observed Molecular Weight
173
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NZN5
Isotype
Rabbit IgG

Popular Products