APOBEC3A Polyclonal Antibody

• Background :

  APOBEC3A is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.

• Description :

  Rabbit Anti-APOBEC3A Polyclonal Antibody

• Product Name Alternative :

  APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1

• Gene ID :

  200315

• Accession Number :

  P31941

• Reactivity :

  Human

• Immunogen :

  Synthesized peptide derived from the Internal region of human APOBEC3A at AA rangle: 40-120

• Clonality :

  Polyclonal

• Tag :

  Probable DNA dC->dU-editing enzyme APOBEC-3A

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  26kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.

• Other Product Names :

  APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P31941

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG