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Nesprin-3 Polyclonal Antibody

CAT: 0749-ABP53964-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53964-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
Description
Rabbit Anti-Nesprin-3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Gene ID
161176
Accession Number
Q6ZMZ3
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Nesprin-3 at AA rangle: 140-220
Clonality
Polyclonal
Tag
Nesprin-3
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
115kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Nesprin-3 Polyclonal Antibody detects endogenous levels of Nesprin-3 protein.
Observed Molecular Weight
130
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6ZMZ3
Isotype
Rabbit IgG

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