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COL7A1 Polyclonal Antibody

CAT: 0749-ABP53750-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53750-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
COL7A1 encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
Description
Rabbit Anti-COL7A1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen
Gene ID
1294
Accession Number
Q02388
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human COL7A1 at AA rangle: 1810-1890
Clonality
Polyclonal
Tag
Collagen alpha-1 (VII) chain
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
COL7A1 Polyclonal Antibody detects endogenous levels of COL7A1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q02388
Isotype
Rabbit IgG

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