Products for Research Use Only
RegisterLogin

COL4A1 Polyclonal Antibody

CAT: 0749-ABP51024-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP51024-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
COL4A1 encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in COL4A1 cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-COL4A1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
COL4A1; Collagen alpha-1 (IV) chain
Gene ID
1282
Accession Number
P02462
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human COL4A1 at AA range: 30-110
Clonality
Polyclonal
Tag
Collagen alpha-1 (IV) chain
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
160kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
COL4A1 Polyclonal Antibody detects endogenous levels of COL4A1 protein.
Observed Molecular Weight
160
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
COL4A1; Collagen alpha-1 (IV) chain
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P02462
Isotype
Rabbit IgG

Related Products

CatalogName
PPT-11969Human COL4A1 Recombinant Protein
ANT-11603-100ugCOL7A1 Polyclonal Antibody
ANT-11598-100ugCOL2A1 Polyclonal Antibody
ANT-11592-50ugCOL14A1 Polyclonal Antibody
ABP53741-01COL4A5 Polyclonal Antibody
ABP53750-01COL7A1 Polyclonal Antibody
ABP51026-01COL5A1 Polyclonal Antibody
ABP56479-01COL14A1 Polyclonal Antibody
ABP51025-01COL4A6 Polyclonal Antibody
ABP53751-01COL9A1 Polyclonal Antibody

Alternative Products

CatalogName
MBS8592070-01COL4A1 Polyclonal Antibody
APRab09185-01COL4A1 Rabbit Polyclonal Antibody

Popular Products