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Val-Cit-PABC-DOX

CAT: 0931-T88212-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88212-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1022094-34-3
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
Val-Cit-PABC-DOX (compound 10109), a conjugate based on epsilon-poly-L-lysine, functions as an agent-linker for ADC, employing Doxorubicin—an inhibitor of both DNA topoisomerase I and II—as the linked agent via the Val-Cit-PABC linker.
Smiles
OC=1C2=C([C@@H](O[C@H]3C[C@H](NC(OCC4=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C4)=O)[C@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C5C1C(=O)C=6C(C5=O)=C(OC)C=CC6
Molecular Formula
C46H56N6O16
Molecular Weight
948.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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