AChRβ1 Polyclonal Antibody

CAT: 0749-ABP53644-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP53644-01Size:30 µL
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Background
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. CHRNB encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
Description
Rabbit Anti-AChRβ1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CHRNB1; ACHRB; CHRNB; Acetylcholine receptor subunit beta
Gene ID
1140
Accession Number
P11230
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human AChRβ1 at AA rangle: 10-90
Clonality
Polyclonal
Tag
Acetylcholine receptor subunit beta
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
55kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
AChRβ1 Polyclonal Antibody detects endogenous levels of AChRβ1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
CHRNB1; ACHRB; CHRNB; Acetylcholine receptor subunit beta
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P11230
Isotype
Rabbit IgG

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