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AChRα3 Polyclonal Antibody

CAT: 0749-ABP50583-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50583-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHRNA3 encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. CHRNA3 encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein (cholinergic receptor nicotinic alpha 3 subunit) is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Description
Rabbit Anti-AChRα3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
Gene ID
1136
Accession Number
P32297
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human AChRα3
Clonality
Polyclonal
Tag
Neuronal acetylcholine receptor subunit alpha-3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
57kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
AChRα3 Polyclonal Antibody detects endogenous levels of AChRα3 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P32297
Isotype
Rabbit IgG

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