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GRIP-1 Polyclonal Antibody

CAT: 0749-ABP53487-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53487-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD) .
Description
Rabbit Anti-GRIP-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Glutamate receptor interacting protein 1; glutamate receptor-interacting protein 1; GRIP; GRIP-1
Gene ID
10499
Accession Number
Q15596
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human GRIP-1 around the non-phosphorylation site of S736
Clonality
Polyclonal
Tag
Nuclear receptor coactivator 2
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GRIP-1 Polyclonal Antibody detects endogenous levels of GRIP-1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
Glutamate receptor interacting protein 1; glutamate receptor-interacting protein 1; GRIP; GRIP-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q15596
Isotype
Rabbit IgG

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