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Vav3 Polyclonal Antibody

CAT: 0749-ABP53477-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53477-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Description
Rabbit Anti-Vav3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Gene ID
10451
Accession Number
Q9UKW4
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human Vav3 around the non-phosphorylation site of Y173
Clonality
Polyclonal
Tag
Guanine nucleotide exchange factor VAV3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
98kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Vav3 Polyclonal Antibody detects endogenous levels of Vav3 protein.
Observed Molecular Weight
98
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UKW4
Isotype
Rabbit IgG

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