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ANG I Polyclonal Antibody

CAT: 0749-ABP53274-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53274-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Angiogenin encoded by ANG is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
Description
Rabbit Anti-ANG I Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ANG; RNASE5; Angiogenin; Ribonuclease 5; RNase 5
Gene ID
283
Accession Number
P03950
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human ANG I
Clonality
Polyclonal
Tag
Angiogenin
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
17kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ANG I Polyclonal Antibody detects endogenous levels of ANG I protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
ANG; RNASE5; Angiogenin; Ribonuclease 5; RNase 5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P03950
Isotype
Rabbit IgG

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