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Chymase Polyclonal Antibody

CAT: 0749-ABP52854-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52854-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CMA1 encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.
Description
Rabbit Anti-Chymase Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
Gene ID
1215
Accession Number
P23946
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Chymase
Clonality
Polyclonal
Tag
Chymase
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
27kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Chymase Polyclonal Antibody detects endogenous levels of Chymase protein.
Observed Molecular Weight
27
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P23946
Isotype
Rabbit IgG

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