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PAOX Polyclonal Antibody

CAT: 0749-ABP52829-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52829-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PAOX (Polyamine Oxidase (Exo-N4-Amino) ) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. Gene Ontology (GO) annotations related to this gene include receptor binding and polyamine oxidase activity. An important paralog of this gene is KDM1B. Flavoenzyme which catalyzes the oxidation of N (1) -acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N (1) -acetylspermidine to putrescine. Substrate specificity: n (1) -acetylspermine = N (1) -acetylspermidine > N (1), N (12) -diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Description
Rabbit Anti-PAOX Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PAOX; PAO; Peroxisomal N (1) -acetyl-spermine/spermidine oxidase; Polyamine oxidase
Gene ID
196743
Accession Number
Q6QHF9
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human PAOX at AA range: 260-340
Clonality
Polyclonal
Tag
Peroxisomal N (1) -acetyl-spermine
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PAOX Polyclonal Antibody detects endogenous levels of PAOX protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:40000; IF 1:50-200
Other Product Names
PAOX; PAO; Peroxisomal N (1) -acetyl-spermine/spermidine oxidase; Polyamine oxidase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6QHF9
Isotype
Rabbit IgG

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