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Nup88 Polyclonal Antibody

CAT: 0749-ABP52804-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52804-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
Rabbit Anti-Nup88 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
NUP88; Nuclear pore complex protein Nup88; 88 kDa nucleoporin; Nucleoporin Nup88
Gene ID
4927
Accession Number
Q99567
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Nup88 at AA range: 330-410
Clonality
Polyclonal
Tag
Nuclear pore complex protein Nup88
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
83kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Nup88 Polyclonal Antibody detects endogenous levels of Nup88 protein.
Observed Molecular Weight
83
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
NUP88; Nuclear pore complex protein Nup88; 88 kDa nucleoporin; Nucleoporin Nup88
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99567
Isotype
Rabbit IgG

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