Products for Research Use Only

FTO Polyclonal Antibody

CAT: 0749-ABP52764-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52764-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Description
Rabbit Anti-FTO Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein
Gene ID
79068
Accession Number
Q9C0B1
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human FTO
Clonality
Polyclonal
Tag
Alpha-ketoglutarate-dependent dioxygenase FTO
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
58kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
FTO Polyclonal Antibody detects endogenous levels of FTO protein.
Observed Molecular Weight
58
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9C0B1
Isotype
Rabbit IgG