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SnoN Polyclonal Antibody

CAT: 0749-ABP52474-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52474-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ski-like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB) . In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
Description
Rabbit Anti-SnoN Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SKIL; SNO; Ski-like protein; Ski-related oncogene; Ski-related protein
Gene ID
6498
Accession Number
P12757
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human SnoN at AA range: 590-670
Clonality
Polyclonal
Tag
Ski-like protein
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
77kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.
Observed Molecular Weight
77
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
SKIL; SNO; Ski-like protein; Ski-related oncogene; Ski-related protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P12757
Isotype
Rabbit IgG

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