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PRX III Polyclonal Antibody

CAT: 0749-ABP52267-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52267-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PRDX3 encodes a mitochondrial protein with antioxidant function. Peroxiredoxin 3 is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E.coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of PRDX3 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
Description
Rabbit Anti-PRX III Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PRDX3; AOP1; Thioredoxin-dependent peroxide reductase; mitochondrial; Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog
Gene ID
10935
Accession Number
P30048
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human PRX III
Clonality
Polyclonal
Tag
Thioredoxin-dependent peroxide reductase mitochondrial
Applications
WB, IHC, IP, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
26kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.
Observed Molecular Weight
26
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC:1:50-300; IP 1:50-200; ELISA 1:20000; IF 1:50-200
Other Product Names
PRDX3; AOP1; Thioredoxin-dependent peroxide reductase; mitochondrial; Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P30048
Isotype
Rabbit IgG

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