PDE4C Polyclonal Antibody

• Background :

  Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.

• Description :

  Rabbit Anti-PDE4C Polyclonal Antibody

• Product Name Alternative :

  PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21

• Gene ID :

  5143

• Accession Number :

  Q08493

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from the Internal region of human PDE4C at AA range: 260-340

• Clonality :

  Polyclonal

• Tag :

  CAMP-specific 3',5'-cyclic phosphodiesterase 4C

• Applications :

  WB, ELISA, IHC

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  80kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.

• Observed Molecular Weight :

  80

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

• Other Product Names :

  PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q08493

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG