PDE4B/C/D Polyclonal Antibody

CAT: 0749-ABP52163-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52163-01Size:30 µL
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Background
PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. PDE4D uses different promoters to generate multiple alternatively spliced transcript variants that encode functiona.
Description
Rabbit Anti-PDE4B/C/D Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PDE4B; DPDE4; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43
Gene ID
5144/5142/5143
Accession Number
Q07343/Q08493/Q08499
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human PDE4B/C/D around the non-phosphorylation site of S133/119/190
Clonality
Polyclonal
Tag
CAMP-specific 3',5'-cyclic phosphodiesterase 4D
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
76kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PDE4B/C/D Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein.
Observed Molecular Weight
76
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
PDE4B; DPDE4; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q07343
Isotype
Rabbit IgG

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