PAI-3 Polyclonal Antibody

CAT: 0749-ABP52145-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52145-01Size:30 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.
Description
Rabbit Anti-PAI-3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SERPINA5; PCI; PLANH3; Plasma serine protease inhibitor; Acrosomal serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5
Gene ID
155698
Accession Number
P05154
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human PAI-3 at AA range: 230-310
Clonality
Polyclonal
Tag
Plasma serine protease inhibitor
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
42kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PAI-3 Polyclonal Antibody detects endogenous levels of PAI-3 protein.
Observed Molecular Weight
42
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
SERPINA5; PCI; PLANH3; Plasma serine protease inhibitor; Acrosomal serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P05154
Isotype
Rabbit IgG

Related Products

CatalogName
ABP55456-01PAI-2 Polyclonal Antibody
ABP52144-01PAI-1 Polyclonal Antibody
ANT-14350-100ugSERPINE1 / PAI-1 Polyclonal Antibody
ANT-14350-50ugSERPINE1 / PAI-1 Polyclonal Antibody
ANT-36338-100ugHuman SERPINE1/PAI-1 Antibody
ANT-36746-100ugMouse SERPINE1/PAI-1 Antibody
ABP50544-0114-3-3 ζ Polyclonal Antibody
ABP50546-0114-3-3 θ/τ Polyclonal Antibody
ABP56526-0114-3-3 ζ/δ Polyclonal Antibody
ABP56523-0114-3-3 γ Polyclonal Antibody

Alternative Products

CatalogName
RA28475-01PAI-3 Polyclonal Antibody
E53P05509PAI-3 Rabbit Polyclonal Antibody
BS3152-01PAI-3 (L291) polyclonal antibody
41321-01PAI Polyclonal Antibody
MBS8592618-01PAI-1 Polyclonal Antibody
BT-AP06886-01PAI-2 Polyclonal Antibody
MBS8564707-01PAI-3 Antibody

Popular Products