Products for Research Use Only

IRF-3 Polyclonal Antibody

CAT: 0749-ABP51644-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51644-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. Interferon regulatory factor 3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Description
Rabbit Anti-IRF-3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
IRF3; Interferon regulatory factor 3; IRF-3
Gene ID
3661
Accession Number
Q14653
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human IRF-3 around the non-phosphorylation site of S396
Clonality
Polyclonal
Tag
Interferon regulatory factor 3
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
48-55kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
IRF-3 Polyclonal Antibody detects endogenous levels of IRF-3 protein.
Observed Molecular Weight
47
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Other Product Names
IRF3; Interferon regulatory factor 3; IRF-3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14653
Isotype
Rabbit IgG

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