IQGAP1 Polyclonal Antibody

• Background :

  IQGAP1 encodes a member of the IQGAP family. Ras GTPase-activating-like protein IQGAP1 contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

• Description :

  Rabbit Anti-IQGAP1 Polyclonal Antibody

• Product Name Alternative :

  IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

• Gene ID :

  8826

• Accession Number :

  P46940

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human IQGAP1 at AA range: 220-300

• Clonality :

  Polyclonal

• Tag :

  Ras GTPase-activating-like protein IQGAP1

• Applications :

  WB, IHC

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  190kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.

• Observed Molecular Weight :

  190

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300

• Other Product Names :

  IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P46940

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG